Primary insulin-like growth factor-1 (IGF-1) deficiency

**Inclusion terms:** - Acid-labile subunit gene (IGFALS) defect - Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies - Growth hormone insensitivity syndrome (GHIS) - Insulin-like growth factor 1 gene (IGF1) defect - Laron type short stature - Severe primary insulin-like growth factor-1 deficiency (SPIGFD) - Signal transducer and activator of transcription 5B gene (STAT5b) defect