Granuloma inguinale

**Definition:** A disease caused by infection with the gram-negative bacterium Klebsiella granulomatis. It commonly presents with painless genital ulceration following contact with an infected sexual partner. Small, painless nodules appear after an incubation period of about 10–40 days; later the nodules break down to create open, fleshy, oozing ulcers which gradually extend, mutilating the infected tissue. The lesions occur at the region of contact and are typically found on the shaft of the penis, the labia, or the perineum.

**Long definition:** Granuloma inguinale is a bacterial disease caused by Klebsiella granulomatis characterized by ulcerative genital lesions. The ulcers ultimately progress to destruction of internal and external tissue, with extensive leakage of mucus and blood from the lesions.

**Inclusions:** - Donovanosis