Peripheral precocious puberty

**Definition:** Precocious puberty without activation of the GnRH-/gonadotropin axis. It includes gonadal tumours with sex hormone production and it may be part of McCune-Albright's syndrome.

**Inclusions:** - Precocious menstruation

**Exclusions:** - Central precocious puberty - Congenital adrenal hyperplasia - female heterosexual precocious pseudopuberty - male isosexual precocious pseudopuberty