Granuloma or granuloma-like lesions of oral mucosa

**Definition:** This is a specific type of chronic inflammatory response of the oral mucosa characterised by a localised accumulation of epithelioid macrophages, multi nucleate giant cells, and lymphocytes.

**Long definition:** These are formed in response to certain micro-organisms in specific infections (ex. in tuberculosis, leprosy, syphilis), against foreign particles (ex. retained sutures), or as part of the immune response (ex. Crohn's disease or sarcoid). Granulomas associated with tuberculosis are characterized by central necrosis.

**Inclusions:** - denture granuloma