Syndromes with premature ageing appearance as a major feature

**Definition:** A heterogeneous group of hereditary syndromes in which affected individuals do or appear to age at an accelerated rate.

**Inclusions:** - Progeroid syndromes - Cockayne syndrome - Rothmund-Thomson syndrome - Progeria - Kindler syndrome

**Exclusions:** - Xeroderma pigmentosum - Cutis laxa