Perforation of large intestine

**Definition:** Perforation of large intestine is a complete penetration of the colonic wall, often resulting in the leakage of luminal contents into the abdominal cavity. Perforation of large intestine results in the potential for bacterial contamination of the abdominal cavity and peritonitis.

**Exclusions:** - Diverticular disease of large intestine - Ulcerative colitis - Crohn disease - Neoplasms of the large intestine