D000067596Level 7
Interleukin-33
**Definition:** A member of the INTERLEUKIN-1 protein family involved in the maturation of TH2 CELLS and the activation of MAST CELLS; BASOPHILS; EOSINOPHILS and NK CELLS. It is also produced by ENDOTHELIAL CELLS; EPITHELIAL CELLS and FIBROBLASTS; where it can function as an alarmin to modulate immune and inflammatory responses to tissue damage.
**Tree numbers:** - D12.644.276.374.465.850 - D12.776.467.374.465.850 - D23.529.374.465.850
**Synonyms:** - IL33 - IL-33
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