CELF1 Protein

**Definition:** A member of the CELF PROTEINS family which binds GU rich elements (GREs) and CUG-triplet repeats in the 3'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich elements (AREs or EDEN-like) in the 3'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with MYOTONIC DYSTROPHY type 1.

**Tree numbers:** - D12.776.157.725.813.250.500 - D12.776.664.962.813.250.500

**Synonyms:** - BRUNOL2 Protein - CUG Triplet Repeat, RNA-Binding Protein 1 - CUGBP, Elav-Like Family Member 1 Protein - CUGBP1 Protein - Bruno-Like 2 Protein