Everolimus

**Definition:** A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.

**Tree numbers:** - D02.540.505.760.500

**Synonyms:** - 40-O-(2-hydroxyethyl)-rapamycin - SDZ RAD - SDZ-RAD