Podosomes

**Definition:** Actin-rich adhesive structures found at the ventral surface of metazoan ENDOTHELIAL CELLS. When found in cultured cancer cells they are referred to as invadopodia. These are matrix-degrading structures composed of an ACTIN CYTOSKELETON core and an INTEGRINS-containing ring complex.

**Tree numbers:** - A11.284.180.695 - A11.436.275.841

**Synonyms:** - Invadopodia - Invadosomes - Invadopodium