Denosumab

**Definition:** A humanized monoclonal antibody and an inhibitor of the RANK LIGAND, which regulates OSTEOCLAST differentiation and bone remodeling. It is used as a BONE DENSITY CONSERVATION AGENT in the treatment of OSTEOPOROSIS.

**Tree numbers:** - D12.776.124.486.485.114.224.060.782 - D12.776.124.790.651.114.224.060.782 - D12.776.377.715.548.114.224.200.782