D000069579Level 10
Ranibizumab
**Definition:** A recombinant humanized monoclonal antibody fragment that binds VEGF-A to prevent its binding to VEGFR-1 and VEGFR-2 receptors. This activity reduces vessel permeability and angiogenesis in the treatment of neovascular age-related MACULAR DEGENERATION.
**Tree numbers:** - D12.776.124.486.485.114.224.060.868 - D12.776.124.790.651.114.224.060.868 - D12.776.377.715.548.114.224.200.868
**Synonyms:** - RhuFab V2
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