ATP Binding Cassette Transporter, Subfamily G, Member 2

**Definition:** ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.

**Tree numbers:** - D09.400.430.890.020.457.500 - D12.776.157.530.100.228.500 - D12.776.395.550.020.457.500 - D12.776.543.550.192.457.500 - D12.776.543.585.100.228.500

**Synonyms:** - ABCG2 Protein - CD338 Antigen - ABCG2 Transporter - ATP Binding Cassette Transporter, Sub-Family G, Member 2