ADAMTS5 Protein

**Definition:** An ADAMTS protease that contains two C-terminal thrombospondin (TS) motifs. It functions primarily as an aggrecanase, cleaving AGGRECAN in CARTILAGE, and may be involved in the destruction of aggrecan in ARTHRITIS.

**Tree numbers:** - D08.811.277.656.675.374.102.500.875 - D09.400.430.500.500.875 - D12.776.395.033.500.875 - D12.776.860.300.085.875

**Synonyms:** - ADAMTS-5 Protein - ADAMTS5 Protease - ADAMTS11 Protein - Aggrecanase-2 - A Disintegrin And Metalloproteinase With Thrombospondin Motifs 5 Protein