Poly (ADP-Ribose) Polymerase-1

**Definition:** A poly(ADP-ribose) polymerase that contains two ZINC FINGERS in its N-terminal DNA-binding region. It modifies NUCLEAR PROTEINS involved in chromatin architecture and BASE EXCISION REPAIR with POLY ADENOSINE DIPHOSPHATE RIBOSE.

**Tree numbers:** - D08.811.913.400.725.115.690.420

**Synonyms:** - PARP-1 Protein - NAD+ ADP-ribosyltransferase-1 - PARP1 Protein - Poly (ADP-Ribose) Synthase-1