Promyelocytic Leukemia Protein

**Definition:** A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.

**Tree numbers:** - D12.776.624.776.654 - D12.776.660.745 - D12.776.930.713 - D12.776.934.500

**Synonyms:** - TRIM19 Protein - RNF71 Protein