CD48 Antigen

**Definition:** A 40-45 KDa GPI-linked protein in the SLAM family that consists of two IMMUNOGLOBULIN C2-SET DOMAINS. It is expressed on the surface of a variety of cells with immune functions, including THYMOCYTES; mature B-LYMPHOCYTES and T-LYMPHOCYTES; NATURAL KILLER CELLS; DENDRITIC CELLS; MAST CELLS; and EOSINOPHILS. It binds to CD2 and 2B4 (CD244) receptors to activate and modulate the immunologic response.

**Tree numbers:** - D09.400.430.890.448.180 - D09.400.430.890.736.250 - D12.776.395.550.448.180 - D12.776.395.550.736.250 - D12.776.543.484.500.180 - D12.776.543.550.418.180 - D12.776.543.550.746.250 - D12.776.543.750.705.970.250

**Synonyms:** - Signaling Lymphocytic Activation Molecule 2 - Blast1 Antigen - B-Lymphocyte Activation Marker BLAST-1 - MRC OX-45 Antigen - Signal-Transducing Glycoprotein-60 - P41 Antigen - SLAM Family Member 2 - SLAMF2 Protein - BCM1 Surface Antigen - Signaling Lymphocytic Activation Molecule Family Member 2 - Leukocyte Antigen MEM-102