Signaling Lymphocytic Activation Molecule Associated Protein

**Definition:** A signal transducing adaptor protein that contains a single SH2 DOMAIN and is essential for the regulation of SLAM FAMILY RECEPTORS in the immune response. Mutations in the SLAM-associated protein gene have been identified in cases of X-LINKED LYMPHOPROLIFERATIVE DISEASE.

**Tree numbers:** - D12.644.360.024.332 - D12.776.157.057.166 - D12.776.476.024.426

**Synonyms:** - SLAM-Associated Protein - SH2D1A Protein