Autophagy-Related Protein 12

**Definition:** A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes.

**Tree numbers:** - D12.776.094.391 - D12.776.947.125

**Synonyms:** - Ubiquitin-Like Protein ATG12 - ATG12 Protein