Influenza A Virus, H5N8 Subtype

**Definition:** A subtype of INFLUENZA A VIRUS that is highly virulent in poultry and wild birds, but shows varying degrees of pathogenicity in mice. The H5N8 virus subtype has a polybasic amino acid motif at the HA cleavage site which explains its pathogenicity in birds, and expresses surface proteins HEMAGGLUTININ 5 and NEURAMINIDASE 8 which are typical of Highly Pathogenic Avian Influenza viruses.

**Tree numbers:** - B04.820.480.968.405.400.598

**Synonyms:** - Avian Influenza A(H5N8) Virus - H5N8 - H5N8 Bird Flu Virus - H5N8 Influenza Virus - H5N8 subtype - H5N8 Virus - Influenza A(H5N8) Virus