Small Leucine-Rich Proteoglycans

**Definition:** A proteoglycan family (SLRPs) that is defined by a central domain which consists of a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE; VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE residues and may be modified depending on function. SLRPs provide structural support to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics at CELL-MATRIX JUNCTIONS.

**Tree numbers:** - D09.400.430.930.875 - D09.698.735.700 - D12.776.395.650.875 - D12.776.860.300.806

**Synonyms:** - Small Leucine-Rich Repeat Proteoglycan - SLRP Proteoglycans - Small Leucine-Rich Repeat Proteoglycans - Small Leucine Rich Proteoglycan - Small Leucine-Rich Proteoglycan - SLRP Proteoglycan