Transcription Activator-Like Effectors

**Definition:** Virulence factors of pathogenic plant bacteria, such as XANTHOMONAS species, that bind to specific sequences in the PROMOTER REGIONS of host DNA to induce transcription of specific host genes. Variations in the DNA binding domain of TALE family members account for the variations in DNA specificity. The TALE DNA-binding domains are used in various GENETIC TECHNIQUES by fusing them with various DNA modifying enzymes to detect and manipulate sequence-specific targeted DNA sites.

**Tree numbers:** - D12.776.097.890 - D12.776.260.755.700 - D12.776.930.900.550 - D23.946.896.490

**Synonyms:** - Transcription Activator-Like Effector - TAL Effectors - TAL Effector