12E7 Antigen

**Definition:** A cell adhesion molecule that, in humans, is encoded by a gene on the PSEUDOAUTOSOMAL REGION of SEX CHROMOSOMES. It functions in CELL ADHESION of T-LYMPHOCYTES and ROSETTE FORMATION by ERYTHROCYTES. It is also involved in the migration of LEUKOCYTES through the ENDOTHELIUM BASEMENT MEMBRANE. The 12E7 antigen co-localizes with, but functions independently of PECAM-1.

**Tree numbers:** - D09.400.430.890.200.049 - D12.776.395.550.200.049 - D12.776.543.550.200.062 - D23.050.301.350.049

**Synonyms:** - CD99 Molecule - 12E7 Protein - E2 Antigen - CD99 Antigen - Antigens, CD99 - T-Cell Surface Glycoprotein E2 - MIC2 Protein