Stromal Interaction Molecule 1

**Definition:** A stromal interaction molecule that functions in the regulation of calcium influx following depletion of intracellular calcium in the ENDOPLASMIC RETICULUM. It translocates to the plasma membrane upon calcium depletion where it activates the CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL ORAI1.

**Tree numbers:** - D12.776.157.125.806.500 - D12.776.543.875.500

**Synonyms:** - STIM1 Protein