D000071739Level 8

Calcium Release Activated Calcium Channels

**Definition:** Specialized calcium channels that localize to the ENDOPLAMSIC RETICULUM and PLASMA MEMBRANE. They contain the pore subunit ORAI1 PROTEIN which is activated by STROMAL INTERACTION MOLECULES upon intracellular calcium depletion.

**Tree numbers:** - D12.776.157.530.400.150.740 - D12.776.543.550.450.150.740 - D12.776.543.585.400.150.740

**Synonyms:** - Calcium Release-Activated Channels - CRAC Channels - Calcium Release-Activated Calcium Channels - CRAC Channel - Calcium Release Activated Calcium Channel

GET/api/v1/systems/mesh/nodes/D000071739

Official DownloadPublic Domain (US Government)Source

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D000071740ORAI1 Protein

D000071741ORAI2 Protein

Cross-system equivalences0

No cross-system equivalences mapped for this node.

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