World Of Taxonomy
D000071796Level 5

SMARCB1 Protein

**Definition:** A component of the SWI-SNF CHROMATIN REMODELING complex that functions as a PROTEIN PHOSPHATASE 1 regulator and to stabilize CHROMATIN at PROMOTER REGIONS. It is important for regulating CELL PROLIFERATION and CELL DIFFERENTIATION. Mutations in the SMARCB1 gene are associated with malignant RHABDOID TUMORS.

**Tree numbers:** - D12.776.260.716 - D12.776.660.235.650 - D12.776.664.235.900 - D12.776.930.809

**Synonyms:** - Swi-Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily B Member 1 - BRG1-Associated Factor 47 Protein - BAF47 Protein - SNF5 Homolog Protein - Integrase Interactor 1 Protein

GET/api/v1/systems/mesh/nodes/D000071796
Official DownloadPublic Domain (US Government)Source

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