Superoxide Dismutase-1

**Definition:** A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.

**Tree numbers:** - D08.811.682.881.500

**Synonyms:** - Cu-Zn Superoxide Dismutase - Cuprozinc Superoxide Dismutase - SOD-1 Protein - SOD1 Protein - Superoxide Dismutase 1