Inositol Polyphosphate 5-Phosphatases

**Definition:** Phosphoinositide phosphatases that catalyze the removal of the 5' phosphate from INOSITOL 1,4,5-TRISPHOSPHATE or myo-inositol 1,3,4,5-tetrakisphosphate, resulting in inositol 1,4-bisphosphate and phosphate. They have important functions in the metabolism of INOSITOL PHOSPHATES and inositol 1,4,5-trisphosphate signaling pathways such as CALCIUM SIGNALING.

**Tree numbers:** - D08.811.277.352.650.624.500

**Synonyms:** - Inositol-Polyphosphate 5-Phosphatase - Inositol 5-Phosphatase - Inositol Polyphosphate 5-Phosphatase - Inositol Triphosphate 5-Phosphatase