Connexin 26

**Definition:** A gap junction protein encoded by the Gap Junction Beta 2 or GJB2 gene. In the cochlea and epidermis, its hexamers form channels between cells that open to allow cell-to-cell diffusion of small molecules as well as recycling of potassium. Mutations in Connexin 26 are associated with congenital SENSORINEURAL HEARING LOSS.

**Tree numbers:** - D12.776.543.585.250.100

**Synonyms:** - Connexin Cx26 - beta2 Connexin - Connexin beta-2