Syk Kinase

**Definition:** An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.

**Tree numbers:** - D08.811.913.696.620.682.725.650 - D12.776.476.568.650

**Synonyms:** - SYK Tyrosine Kinase - Spleen Tyrosine Kinase