Pancreatitis-Associated Proteins

**Definition:** C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker.

**Tree numbers:** - D12.776.503.280.578 - D23.050.285.733 - D23.101.140.780

**Synonyms:** - Regenerating Islet-Derived Proteins - Regenerating Islet-Derived Protein