Trisomy 13 Syndrome

**Definition:** A chromosome disorder associated with TRISOMY of all or part of CHROMOSOME 13. Clinical manifestations include CONGENITAL HEART DEFECTS (e.g., PATENT DUCTUS ARTERIOSUS), facial malformations (e.g., CLEFT LIP; CLEFT PALATE; COLOBOMA; MICROPHTHALMIA); HYPOTONIA, digit malformations (e.g., POLYDACTYLY or SYNDACTYLY), and SEIZURES and severe INTELLECTUAL DISABILITY associated with NERVOUS SYSTEM MALFORMATIONS.

**Tree numbers:** - C10.597.606.360.835 - C14.240.400.970 - C14.280.400.970 - C16.131.077.919 - C16.131.240.400.965 - C16.131.260.923 - C16.320.180.923

**Synonyms:** - Bartholin-Patau Syndrome - Chromosome 13 Trisomy Syndrome - Patau's Syndrome - Trisomy 13 Syndromes - Patau Syndrome