T-Cell Acute Lymphocytic Leukemia Protein 1

**Definition:** A basic helix-loop-helix transcription factor that plays a critical role in HEMATOPOIESIS and as a positive regulator in the differentiation of ERYTHROID CELLS. Chromosome translocations involving the TAL-1 gene are associated with T-CELL ACUTE LYMPHOCYTIC LEUKEMIA.

**Tree numbers:** - D12.776.260.103.829 - D12.776.624.664.700.960 - D12.776.930.125.829

**Synonyms:** - TAL1 Transcription Factor - TAL-1 Protein