World Of Taxonomy
D000074001Level 7

Intercellular Adhesion Molecule-3

**Definition:** A membrane glycoprotein and cell adhesion molecule expressed by LEUKOCYTES that contains multiple Ig-like domains. It is a ligand for LFA-1 (integrin alphaLbeta2) and integrin alpha-D/beta-2. Its interaction with LFA-1 may play a role in the PHAGOCYTOSIS of NEUTROPHILS by MACROPHAGES following APOPTOSIS.

**Tree numbers:** - D09.400.430.890.200.494 - D12.776.395.550.200.494 - D12.776.543.550.200.494 - D23.050.301.350.494

**Synonyms:** - ICAM3 - ICAM-3 - CD50 Antigen - CDw50 Antigen - Antigens, CD50

GET/api/v1/systems/mesh/nodes/D000074001
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