DNA Polymerase gamma

**Definition:** A DNA-directed DNA polymerase that functions in the replication of MITOCHONDRIAL DNA. Mutations in the gene that encodes this enzyme (POLG) are associated with some forms of OPHTHALMOPLEGIA, CHRONIC EXTERNAL PROGRESSIVE.

**Tree numbers:** - D08.811.913.696.445.308.300.169 - D12.776.575.280

**Synonyms:** - DNA Polymerase Subunit gamma-1 - PolG-alpha - Mitochondrial DNA Polymerase