ATP Binding Cassette Transporter, Subfamily D

**Definition:** A sub-family of ATP-binding cassette transporters that localize to the membranes of PEROXISOMES; ENDOPLASMIC RETICULUM; and LYSOSOMES. Members contain a transmembrane domain in their N-terminal half and generally function as homodimers in the transport of LIPIDS; BILE ACIDS; and VITAMIN B12. Mutations in some ABCD transporter genes are associated with PEROXISOMAL DISORDERS.

**Tree numbers:** - D09.400.430.890.020.419 - D12.776.157.530.100.209 - D12.776.395.550.020.419 - D12.776.543.550.192.419 - D12.776.543.585.100.209

**Synonyms:** - ATP Binding Cassette Transporter, Sub-Family D - ABC Transporter Subfamily D - ABCD Transporters - ABCD Proteins