Solute Carrier Organic Anion Transporter Family Member 1B3

**Definition:** A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.

**Tree numbers:** - D12.776.157.530.450.074.500.781.875 - D12.776.157.530.937.905 - D12.776.543.585.450.074.500.875.875 - D12.776.543.585.937.950

**Synonyms:** - OATP8 Protein - SLC21A8 Protein - Liver-Specific Organic Anion Transporter-2 - OATP1B3 Protein - Solute Carrier Family 21 Member 8 Protein - SLCO1B3 Protein