Short Chain Dehydrogenase-Reductases

**Definition:** A large family of oxidoreductases that are predominantly NAD- or NADP-dependent and 250 to 350 amino acids in length. They generally consist of two PROTEIN DOMAINS: A catalytic N-terminal domain that binds the substrate, and a C-terminal coenzyme-binding domain.

**Tree numbers:** - D08.811.682.047.820.900

**Synonyms:** - Short Chain Dehydrogenases - Short Chain Dehydrogenase Family - Short-Chain Alcohol Dehydrogenases - Short Chain Dehydrogenase Superfamily - Short Chain Dehydrogenase - Short-Chain Alcohol Dehydrogenase - Short Chain Dehydrogenase-Reductase