NADPH Oxidase 1

**Definition:** An NADPH oxidase that functions as a voltage-gated proton channel expressed by PHAGOCYTES, especially in the colon. It regulates intracellular pH, generates SUPEROXIDES upon activation by PHAGOCYTOSIS, and may play a role in INNATE IMMUNITY.

**Tree numbers:** - D08.811.682.608.575.750 - D12.776.331.894.750 - D12.776.543.653.750

**Synonyms:** - NOX1 Protein - Mitogenic Oxidase 1