NADPH Oxidase 4

**Definition:** An NADPH oxidase that is strongly expressed in the kidney. It forms a complex with CYBA-P22PHOX and produces intracellular SUPEROXIDES that may regulate cellular signaling in APOPTOSIS; BONE RESORPTION; and NF-KAPPA B activation.

**Tree numbers:** - D08.811.682.608.575.937 - D12.776.331.894.937 - D12.776.543.653.937

**Synonyms:** - Renox NAD(P)H Oxidase - Renal NAD(P)H Oxidase - Nox4 Protein