rhoC GTP-Binding Protein

**Definition:** A rho GTP-binding protein that is prenylated (see PROTEIN PRENYLATION) at its C-terminus and cycles between the cytoplasm and plasma membrane, linking receptor signaling pathways with assembly of FOCAL ADHESIONS; STRESS FIBERS; and contractile ring formation during CYTOKINESIS. It is overexpressed in proliferating and metastatic tumor cells.

**Tree numbers:** - D08.811.277.040.330.300.400.700.650 - D12.776.157.325.515.700.650 - D12.776.476.338.400.700.650

**Synonyms:** - ras Homolog Family Member C - rhoC GTPase