Myeloid Ecotropic Viral Integration Site 1 Protein

**Definition:** A TALE-type homeodomain protein and transcription factor that functions as a regulator of PAX6 PROTEIN expression and as an activator of PLATELET FACTOR 4 gene expression. It is essential for hematopoiesis, differentiation of MEGAKARYOCYTES, and vascular patterning. It may also have a role in the induction of myeloid leukemias.

**Tree numbers:** - D12.776.260.400.483 - D12.776.930.462

**Synonyms:** - Homeobox Protein MEIS1 - Meis1 Protein - Meis-1 Protein - Meis1 Transcription Factor