Smoldering Multiple Myeloma

**Definition:** An asymptomatic and slow-growing PLASMA CELL dyscrasia characterized by presence of MYELOMA PROTEINS and clonal bone marrow plasma cells without end-organ damage (e.g., renal impairment). It is distinguished from MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE by a much higher risk of progression to symptomatic MULTIPLE MYELOMA.

**Tree numbers:** - C04.834.794 - C15.378.147.542.820 - C15.378.147.780.838 - C20.683.460.820 - C20.683.780.838

**Synonyms:** - Asymptomatic Multiple Myeloma - Smoldering Myeloma