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D000075370Level 5

Receptors for Activated C Kinase

**Definition:** Receptors for PROTEIN KINASE C that consist of seven WD40 REPEATS. They function in a wide variety of cellular and physiologic processes including the assembly of signaling complexes, protein translation, cell growth and proliferation, APOPTOSIS, and MUSCARINIC RECEPTOR transport. RACK1 depends on protein kinase C activity to translocate from the perinuclear region to the cell periphery and associates with the plasma membrane through interactions with KERATIN-1 and INTEGRIN BETA-1.

**Tree numbers:** - D12.776.826.313

**Synonyms:** - GNB2-RS1 Protein - Receptor of Activated C Kinase 1 - GNB2L1 Protein - Protein Kinase C Receptor - Protein Kinase C Receptors - Receptor, Protein Kinase C - Receptor for Activated C Kinase - RACK1 Protein

GET/api/v1/systems/mesh/nodes/D000075370
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