Intraepithelial Lymphocytes

**Definition:** T Lymphocytes with limited diversity of receptors (e.g., ALPHA E INTEGRINS) in the epidermis of the skin and the mucosal linings. They recognize common microbes via T-CELL RECEPTORS and PATHOGEN-ASSOCIATED MOLECULAR PATTERN MOLECULES and function as effector cells for INNATE IMMUNITY. Activation of intraepithelial lymphocytes is a marker for various gastrointestinal diseases (e.g., CELIAC DISEASE; HAIRY CELL LEUKEMIA; and ENTEROPATHY-ASSOCIATED T-CELL LYMPHOMA).

**Tree numbers:** - A11.118.637.555.567.550.500.050 - A11.118.637.555.567.569.500.050 - A15.145.229.637.555.567.550.500.050 - A15.145.229.637.555.567.569.500.050 - A15.382.490.555.567.550.500.050 - A15.382.490.555.567.569.500.050

**Synonyms:** - Intraepithelial Lymphocyte - Gamma Delta T Cells - Gamma Delta T Lymphocytes - Intraepithelial T Lymphocytes - Mucosal T Lymphocytes - Mucosal T Cells - Intraepithelial T Cells - Gamma Delta T Lymphocyte - Intraepithelial T Cell - Intraepithelial T Lymphocyte - Mucosal T Cell - Gamma Delta T Cell - Mucosal T Lymphocyte