Myristoylated Alanine-Rich C Kinase Substrate

**Definition:** A membrane and ACTIN CYTOSKELETON associated, N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation and poly(ADP)-ribosylation inhibit its F-ACTIN crosslinking activity; phosphorylation also causes MARCKS to relocate from the membrane to cytoplasm.

**Tree numbers:** - D05.750.078.730.556 - D12.644.360.537 - D12.776.157.142.375 - D12.776.157.687.496 - D12.776.220.525.556 - D12.776.476.539 - D12.776.543.637 - D12.776.660.720.496

**Synonyms:** - MARCKS Protein - ACAMP-81