D000077155Level 6
Granulins
**Definition:** Small, cysteine-rich peptides generated by the proteolytic cleavage of progranulin. Granulin peptides are each composed of a granulin-motif, while paragranulin is composed of a half-granulin motif. The mammalian granulins are named granulin 1-7 for their sequence order in the progranulin propeptide, and are alternately named granulin G, F, B, A, C, D, and E; or epithelin 7, 6, 2, 1, 3, 4, and 5, i.e. granulin 1 aka granulin G aka epithelin 7, etc.
**Tree numbers:** - D06.472.699.682.500 - D12.644.276.917.500 - D12.776.467.917.500 - D23.529.917.500
**Synonyms:** - Granulin - Epithelin - Epithelins - Granulin Peptides
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