Decitabine

**Definition:** An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.

**Tree numbers:** - D02.145.150.500 - D03.383.742.680.245.217.500 - D13.570.685.245.217.500 - D13.570.800.286.300.500

**Synonyms:** - 5-Azadeoxycytidine - AzadC Compound - 5-Aza-2'-deoxycytidine - 5-AzadC - 2'-Deoxy-5-azacytidine - 5AzadC