Nasopharyngeal Carcinoma

**Definition:** A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes.

**Tree numbers:** - C04.557.470.200.623 - C04.588.443.665.710.650.500 - C07.550.350.650.500 - C07.550.745.650.500 - C09.647.710.650.500 - C09.775.350.650.500 - C09.775.549.650.500