Abciximab

**Definition:** A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.

**Tree numbers:** - D12.644.541.500.650.125 - D12.776.124.486.485.114.224.060.125 - D12.776.124.486.485.680.650.125 - D12.776.124.790.651.114.224.060.125 - D12.776.124.790.651.680.650.125 - D12.776.377.715.548.114.224.200.125 - D12.776.377.715.548.680.650.125

**Synonyms:** - Chimeric 7E3 Fab - c7E3 Fab